Conventional cervical smears were better than monolayer cytology or human papillomavirus testing for detecting cervical intraepithelial neoplasia

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Conventional cervical smears were better than monolayer cytology or human papillomavirus testing for detecting cervical intraepithelial neoplasia

Description of tests and diagnostic standard All women were evaluated by the 3 methods (CCS test, MLC, and HPV testing), and by colposcopy followed by biopsy if abnormalities were detected. After the CCS test, the remaining portion of the sample was used for the monolayer slide and for HPV testing. Smear abnormalities were classified into 5 ordered categories (negative, atypical squamous/glandu...

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Conventional cervical smears were better than monolayer cytology or human papillomavirus testing for detecting cervical intraepithelial neoplasia

and commentary also appear in ACP Journal Club. Diagnosis EBM Volume 8 November/December 2003 187 www.evidence-basedmedicine.com

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Cross sectional study of conventional cervical smear, monolayer cytology, and human papillomavirus DNA testing for cervical cancer screening.

OBJECTIVES To compare the sensitivity, specificity, and interobserver reliability of conventional cervical smear tests, monolayer cytology, and human papillomavirus testing for screening for cervical cancer. DESIGN Cross sectional study in which the three techniques were performed simultaneously with a reference standard (colposcopy and histology). SETTING Public university and private prac...

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Posttreatment human papillomavirus testing for residual or recurrent high-grade cervical intraepithelial neoplasia: a pooled analysis

OBJECTIVE We conducted a pooled analysis of published studies to compare the performance of human papillomavirus (HPV) testing and cytology in detecting residual or recurrent diseases after treatment for cervical intraepithelial neoplasia grade 2 or 3 (CIN 2/3). METHODS Source articles presenting data on posttreatment HPV testing were identified from the National Library of Medicine (PubMed) ...

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Cervical intraepithelial neoplasia in postmenopausal women with negative cervical cytology.

Cervical intraepithelial neoplasia in postmenopausal women with negative cervical cytology Four cases of cervical intraepithelial neoplasia were detected among 50 postmenopausal women in whom cytological examination of a cervical smear yielded negative results, indicating the need for cytological surveillance of women into old age. Cytological and colposcopic examination of the cervix was perfo...

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ژورنال

عنوان ژورنال: Evidence-Based Medicine

سال: 2003

ISSN: 1356-5524

DOI: 10.1136/ebm.8.6.187